RESOURCES
A 2-year follow-up study of T-PEMF
Treatment-resistant depression
Bech P, Lindberg L, Straasø B, Larsen ER, made a 2-year follow-up study to evaluate the effect of repeated transcranial pulsating electromagnetic fields (T-PEMF) augmentation in patients who had achieved remission but later on relapsed, as well as to identify factors contributing to treatment-resistant depression in patients who did not respond to T-PEMF.
T-PEMF has an effect among patients who relapsed after remission with the first series of T-PEMF.
Double Blind tACS for MDD
Targeting alpha oscillations
Major depressive disorder (MDD) is one of the most common psychiatric disorders, but pharmacological treatments are ineffective in a substantial fraction of patients and are accompanied by unwanted side effects. Here we evaluated the feasibility and efficacy of transcranial alternating current stimulation (tACS) at 10 Hz, which we hypothesized would improve clinical symptoms by renormalizing alpha oscillations in the left dorsolateral prefrontal cortex (dlPFC).
Evidence from the ELECT-TDCS trial
Anti-Depressant Effects
Transcranial direct current stimulation (tDCS) is a promising intervention for major depression. However, its clinical effects are heterogeneous. We investigated, in a subsample of the randomized, clinical trial Escitalopram versus Electrical Current Therapy for Depression Study (ELECT-TDCS), whether the volumes of left and right prefrontal cortex (PFC) and anterior cingulate cortex (ACC) were associated with prefrontal tDCS response.
Cranial Electrotherapy Stimulation (CES)
A Safe Neuromedical Treatment for Anxiety, Depression, or Insomnia
Electronic therapeutic devices can actively reduce the number of med- ication errors by reducing the amount of medication needed to treat anxiety, depression, insomnia, and pain. Among the electromedical devices available to the ordinary office practice of general medicine is the cranial electrotherapy stimulation (CES) device.
Transcranial Electrical Stimulation (TES)
Behavioural and Neurophysiological Effects
Transcranial direct current stimulation (tDCS) has been shown to improve cognition in healthy and neuropsychiatric populations. Recent research has suggested that transcranial random noise stimulation (tRNS) may be more effective at modulating cognition. However, there is limited research directly comparing the efficacy of these two methods, and their precise neurophysiological underpinnings remain unclear.
Pulsed Electromagnetic Field Exposure
Alzheimer’s and Parkinson’s disease
Electromagnetic fields are emerging as a potential alternative to the pharmacological treatments in several inflammatory related pathologies. Previous studies have tried to clarify the mechanisms of interaction between low-frequency electromagnetic fields and biological system
It has been reported a protective effect of electromagnetic field exposure in animal models of neurodegenerative diseases.
Military traumatic brain injury
Alzheimer’s & Dementia
Military mild traumatic brain injury (mTBI) differs from civilian injury in important ways. Although mTBI sustained in both military and civilian settings are likely to be underreported, the combat theater presents additional obstacles to reporting and accessing care. The impact of blast forces on the nervous system may differ from non-blast mechanisms, mTBI although studies comparing the neurologic and cognitive sequelae in mTBI survivors have not provided such evidence.
Alpha Power Increase after a-tACS
Reflects Plastic Changes Rather Than Entrainment
Periodic stimulation of occipital areas using transcranial alternating current stimulation (tACS) at alpha (a) frequency (8e12 Hz) enhances electroencephalographic (EEG) a-oscillation long after tACS-offset.
We tested to what extent plasticity can account for tACS-aftereffects when controlling for entrainment “echoes.”
Vagus nerve stimulation
Enhances Extinction of Conditioned Fear
Subjects with PTSD show impaired extinction of conditioned fear, which is associated with decreased vmPFC control over amygdala activity. VNS enhances memory consolidation in both rats and humans, and pairing VNS with exposure to conditioned cues enhances the consolidation of extinction learning in rats. Here we investigated whether pairing VNS with extinction learning facilitates plasticity between the IL medial prefrontal cortex and the BLA.
Pairing Vagus Nerve Stimulation
Reorganizes Primary Motor Cortex
Repeatedly Pairing Vagus Nerve Stimulation with a Movement Reorganizes Primary Motor Cortex. If mechanisms regulating cortical plasticity are common to sensory and motor cortices, then methods generating plasticity in sensory cortex should be effective in motor cortex. Repeatedly pairing a tone with a brief period of vagus nerve stimulation (VNS) increases the proportion of primary auditory cortex responding to the paired tone
Variability in Vagal Control
Response Inhibition Under Stress
Dynamic intra-individual variability (IIV) in cardiac vagal control across multiple situations is believed to contribute to adaptive cognition under stress; however, a dearth of research has empirically tested this notion.
Response inhibition was measured as the correct rejection (CR) of friendly targets during the low and high stress conditions.
Vagus nerve stimulation
Treatment-Resistant Depression
Vagus Nerve Stimulation (VNS) is emerging as one of the neuro- stimulation techniques in the armamentarium of psychiatrists to treat treatment-resistant depression (TRD). VNS has been approved in Europe for drug resistant epilepsy since 1994 and was approved in 2005 for adjunctive treatment of chronic or recurrent depression in patients who are in a treatment-resistant or treatment-intolerant major depressive episode.
External Resources
Click on the logo below to be redirected to the website.
WellSpace is not affiliates of any of these sites, we add these as options for our valued patients.
DRUG REHAB SERVICES IN CANADA
Fertility Secrets of the Female Body
Distress Centres of Greater Toronto. 24-hour support